Washington |3 months ago
Study unlocks mysteries about Alzheimer's
Monday, 23 December 2013 | http://www.nerve.in/news:2535002021338 | channel: Americas
|"The LEC is considered to be a gateway to the hippocampus, which plays a key role in the consolidation of long-term memory, among other functions. If the LEC is affected, other aspects of the hippocampus will also be affected, Small added."|
Washington, Dec 23 - Scientists have shed light on the three essential puzzles regarding Alzheimer's, a science journal reported.
Using high-resolution functional magnetic resonance imaging - in patients with Alzheimer's disease, Columbia University Medical Center - researchers have clarified three fundamental issues about Alzheimer's: where it starts, why it starts there, and how it spreads.
The findings could improve early detection of the disease, when drugs may be most effective. The study was published in the online edition of the journal Nature Neuroscience, reports Science Daily.
It has been known for years that Alzheimer's starts in a brain region known as the entorhinal cortex, said senior co-author Scott A. Small, director of the Alzheimer's Disease Research Center.
But this study is the first to show in living patients that it begins specifically in the lateral entorhinal cortex, or LEC, he said.
The LEC is considered to be a gateway to the hippocampus, which plays a key role in the consolidation of long-term memory, among other functions. If the LEC is affected, other aspects of the hippocampus will also be affected, Small added.
The study also shows that, over the time, Alzheimer's spreads from the LEC directly to other areas of the cerebral cortex, in particular the parietal cortex, a brain region involved in various functions, including spatial orientation and navigation.
|Read more on:|
| ALZHEIMER (4686 views)
COLUMBIA UNIVERSITY (4411 views)
MAGNETIC RESONANCE IMAGING (3391 views)
NEUROSCIENCE (2938 views)
MAGNETIC RESONANCE (1733 views)
HIPPOCAMPUS (1410 views)
COLUMBIA UNIVERSITY MEDICAL CENTER (1211 views)
FUNCTIONAL MAGNETIC RESONANCE IMAGING (652 views)
CEREBRAL CORTEX (281 views)
|Email this story to a friend|
|XML feed for Americas|
All rights reserved for news content. Reproduction, storage or redistribution of Nerve content and articles in any medium is strictly prohibited.
Contact Nerve Staff for any feedback, corrections and omissions in news stories.